1.
RheumatologyNetwork.com: Source of pain in fibromyalgia identified
From the article: “Patients with fibromyalgia syndrome experience chronic pain, which is believed to arise from disordered central processing. … In this study, researchers challenge the prevalent theory of pain in fibromyalgia syndrome, aiming to show that pain over the muscles is linked to elevated intramuscular pressure.”
2.
Northeastern University: Intestinal bacteria could give doctors an objective test for chronic Lyme disease
From the article: “In a study that compared fecal matter from healthy people, intensive care unit patients and [post-treatment Lyme disease syndrome] patients, Lewis and his team determined that people with PTLDS have two distinct differences in microbial levels compared to the other groups – an abundance of a type of bacteria called blautia and a suppression of a type of bacteria called bacteroides.”
3.
Fibromyalgia News Today: Aptinyx reopens enrollment in phase 2 study of NYX-2925 for chronic pain
Note: If you’re unable to access the full article due to Fibromyalgia News Today’s paywall, here’s a link to a summary of the study on ClinicalTrials.gov.
From the article: “Enrollment has resumed for Aptinyx‘s phase 2 clinical trial of NYX-2925, an oral small molecule designed to treat chronic pain in adults with fibromyalgia, the company announced. The study is recommencing after being temporarily suspended in March due to the escalation of COVID-19 in the U.S. Aptinyx has assured patients that the company will take necessary safety precautions to minimize risk to study participants.”
4.
Lyme Disease Association: New dapsone study
From the article: “The study is suggestive that dapsone combination therapy may well characterize both a novel and successful option to treat Borrelia burgdorferi persister cells in the form of biofilm.”
5.
LymeDisease.org: Medical definition of pain updated for first time in four decades
From the article: “…the new pain definition … features a key phrase (shown in boldface): ‘An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage.’ The phrase is important, say the researchers, because it includes types of pain not well understood 40 years ago…”
And an extra…
Vice.com: Why is Amazon tracking opioid use all over the United States?
From the article: “Amazon’s human resources team is tracking opioid usage among the American public as part of a project which involves monitoring internal and external threats to Amazon’s employees and business, according to an internal document obtained by Motherboard.”
This week on FedUpwithFatigue.com…
Amazon Prime Day deals for fibromyalgia, Lyme and similar illnesses
Prime Day is over, and many of the deals have expired, but some items are still discounted.

Check out my favorite Amazon products here!
In case you missed it…
Should you get a flu shot if you have fibromyalgia?

Free masterclass on exercising with chronic illness…
Andrea Wool, fellow fibro warrior and creator of the Autoimmune Strong fitness program, is offering a free masterclass on “How To Do Cardio Without Flare-Up So You Can Live Your Best Life.”
During the class, Andrea discusses how she’s reintroducing cardio back into her fitness routine after recently beating COVID-19 and how you can get started, too.
“I was inspired to teach this class after my own personal bout with COVID, which knocked me off my butt and kept me in bed for a few
months,” says Andrea. “I am now trying to get my cardio back – without flare – and I wanted to share with folks how I am doing it. I am going
to discuss in the class how to get back to walking, running, swimming, biking, gardening and generally just living life without pain and
flare-up.”
You can sign up for a 7-day free trial of Autoimmune Strong here (affiliate link)!
Virtual Pain Conference…
The Pain Society of Alberta (Canada) is hosting a three-day virtual pain conference on Oct. 16-18. Learn more here!

Hi! My son has fibro and small fiber neuropathy and autonomic neuropathy and he turned me on to your blog a couple of years ago and we both find it so informative and are very grateful for you-thank you!
Did you publish something about life coaches a while back? I think my son could benefit from talking with someone that might help him figure out what direction to go with his life. He’s brilliant and did 2 years of bio-engineering but had to stop because of his illnesses and now isn’t sure what to do. Do you have the names of some life coaches that might be helpful or have any other ideas? Thank you for any ideas you may have.
Hi Denice, I personally work w/ Julie Holliday from ME/CFS Self Help Guru. She specializes in coaching for people w/ chronic illnesses like chronic fatigue syndrome, fibromyalgia, Lyme, etc. She offers both individual and group coaching. Here’s a link to her site: https://www.mecfsselfhelpguru.com/coaching