New fibromyalgia research studies (March 2020)

New fibromyalgia research (March 2020) | Fed Up with Fatigue

It’s that time again! Below you’ll find the latest fibromyalgia-related research studies added to ClinicalTrials.gov since my last update in December.

This time around, we have studies involving low-dose naltrexone and cannabis – both emerging treatments for fibromyalgia.

One of my favorite researchers, Dr. Jarred Younger from University of Alabama Birmingham, has introduced a new study in continuation of his work to determine if immune system overreactivity might be the cause of fibromyalgia.

You’ll also find the usual studies regarding diet, exercise and complementary therapies that consistently appear in these updates.

There is one big difference in this update compared to those I’ve published in the past…

There are no Lyme disease studies!

Sadly, that’s because there literally have been NO NEW STUDIES added to the ClinicalTrials.gov database since last November. I kid you not! I’ve been shocked at the lack of movement in Lyme research the past few months. While I acknowledge we’ve never had tons of Lyme research being conducted, it’s appalling to not even have one study over a four-month period.

I sure am hoping this trend will change with the approval of the federal TICK Act last December.

Video version…

I filmed a short 15-minute video highlighting some of the more interesting fibromyalgia studies for those who prefer listening to reading.

Click here or on the photo below to access that video on YouTube.

New fibromyalgia research (March 2020) | Fed Up with Fatigue

Note: All quotations in this post are attributed to ClinicalTrials.gov.


Fibromyalgia and naltrexone: The FINAL study

About 100 patients will participate in a double-blind, placebo-controlled study through Odense University Hospital in Denmark to see if low-dose naltrexone administered over 12 weeks could be an effective treatment for fibromyalgia pain.

(Read more: Using low-dose naltrexone for fibromyalgia)


The innate central nervous system immune response to an experimental immune challenge in people with fibromyalgia

Researcher Dr. Jarred Younger at University of Alabama Birmingham will utilize magnetic resonance spectroscopy “to determine if the innate immune response is dysregulated in people with fibromyalgia compared to healthy controls. … The ultimate goal of this research is to better understand the role of brain inflammation in the pathophysiology of chronic pain and fatigue, which will guide the development of more effective therapies for these conditions.”

(Read more: New UAB study could radically change fibromyalgia treatment as we know it)


Use of KL16-012 in women with fibromyalgia refractary to conventional treatment

Knop Laboratorios in Chile is sponsoring a double-blind, placebo-controlled study to test the effectiveness of a standardized cannabis sativa extract of THC and CBD among 44 women with fibromyalgia.

(Read more: New study shows cannabis is effective for fibromyalgia)


Cognitive profile of patients at the Sagol Center for Hyperbaric Medicine and Research

Assaf-Harofeh Medical Center researchers in Israel are assessing if hyperbaric oxygen treatments improve the neurocognitive function of patients with fibromyalgia, traumatic brain injury, stroke and other conditions. This is a followup study to the center’s previous work, which showed hyperbaric oxygen may be an effective treatment for fibromyalgia.


Hyperbaric oxygen therapy compared to pharmaceutical in fibromyalgia with emotional trauma

This 60-patient study out of Assaf-Harofeh Medical Center in Israel will compare hyperbaric oxygen treatments with standard pharmaceutical treatment (Lyrica and Cymbalta) in women with fibromyalgia who have a past history of emotional trauma.


Effects of photoregulation on pain, functionality and tissue quality in a population suffering from fibromyalgia

University of Malaga researchers in Spain will “evaluate the effectiveness of [photoregulation i.e. red light therapy] on the main symptoms such as pain, quality of life, functionality, catastrophization, self efficacy and quality of soft tissue in the treatment of [fibromyalgia].”

(Read more: Health benefits of red light therapy and how to get it)


Mechanisms of affective touch in chronic pain

Researcher Laura Case at the University of California San Diego will compare “how different types of touch found in massage therapies impact pain perception, and whether these effects differ in individuals with and without chronic pain. …This research will improve our understanding of whether and how massage therapies can benefit pain and health, and whether this differs in people who suffer from chronic pain.”

(Read more: Effectiveness of different styles of massage therapy in fibromyalgia | A systematic review and meta-analysis


Efficacy of multicomponent treatment for fibromyalgia

This study out of Hospital Universitari Vall d’Hebron Research Institute in Spain will compare a multicomponent treatment approach to fibromyalgia utilizing pain neuroscience education, therapeutic exercise, cognitive behavioural therapy and mindfulness training to standard pharmacological treatment.


Veteran ear acupuncture pilot project

“Veterans who have responded well to battlefield acupuncture, a form of auricular acupuncture, in routine clinical practice will be invited to receive education to insert the needles themselves at home” during this 30-person trial conducted at the VA Medical Center in Chillicothe, Ohio, United States.


Evaluation of stigma and related factors in fibromyalgia

Turkish researchers from Gaziosmanpasa Taksim Research and Education Hospital aim “to reveal the presence of stigma in patients diagnosed with fibromyalgia compared with the healthy control group … It is the secondary purpose of this study to determine related factors such as gender, age, educational status, marital status, employment status, income level, pain duration, pain intensity, medications used and social support received from patients’ family and the environment. We hypothesize that this group of patients suffers more stigma and the quality of life decreases due to this stigma.”


Catastrophizing and virtual reality’s impact on pain in patients with fibromyalgia

Researchers from Aalborg University in Denmark plan to evaluate “the potential association between virtual reality, pain catastrophizing thoughts and pain measures in fibromyalgia” using a “cold pressor test” that involves having participants submerge one limb into a tank of cold, circulating water.


Probiotic VSL#3 for the treatment of gastrointestinal symptoms associated to fibromyalgia

Researcher Elena Pita Calandre from Universidad de Granada in Spain will evaluate “the efficacy and tolerability of probiotic VSL#3 for the treatment of gastrointestinal symptoms in patients with fibromyalgia.”

(Read more: People with fibromyalgia show variations in gut bacteria)


Eating behaviours in female patients with fibromyalgia

Gaziosmanpasa Taksim Research and Education Hospital researchers in Turkey will study how the eating behaviors of women with fibromyalgia affect their current health status.

(Read more: The three best diets for fibromyalgia, according to science)


Effect of transcranial direct current stimulation in eating behavior of women with fibromyalgia

Hospital de Clinicas de Porto Alegre researchers in Brazil will “evaluate the association between dopamine receptor-2 (DRD2) Taq1A allele A1 polymorphism (rs1800497) and to observe the possible effect of tDCS [transcranial direct current stimulation] on the dorsolateral prefrontal cortex on homeostatic and hedonistic aspects of eating behavior in women with [fibromyalgia].”


Fibromyalgia and olive oil

University of Jaén researchers in Spain will “investigate the effect of consumption of two types of olive oils with different antioxidant content on thrombosis-related parameters, nitric oxide, inflammation, lipid profile and cortisol as well as on health-related parameters in women with fibromyalgia” in an effort to reduce cardiovascular disease.


Group therapy for fibromyalgia | The effectiveness of mindfulness-based vs. cognitive-behavioral therapy

Researcher Danny Horesh from Bar-Ilan University in Israel will compare mindfulness-based group therapy with cognitive behavioral group therapy among 90 patients with fibromyalgia.


Effectiveness of exercise and patient-centered education on fibromyalgia

Researchers from Escola Superior de Saúde do Instituto Politécnico de Setúbal in Portugal will “compare the effects of an eight-week exercise and patient-centered education program with an eight-week exercise [only] program on disability, pain intensity, health-related quality of life and patient global impression of change” among 60 patients with fibromyalgia.

That’s everything for this research update! Are you excited or hopeful about any of these studies? Share in the comments below!

You might also like…

New fibromyalgia & Lyme disease research (December 2019)

New #fibromyalgia & #Lyme disease research studies (December 2019) | Fed Up with Fatigue


  1. Patricia Jones says

    Thank you Donna very informative. Hopefully someday.


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