Despite the COVID-19 pandemic, fibromyalgia and Lyme research continues – albeit at a slower pace. There aren’t quite as many studies in this quarterly research update from ClinicalTrials.gov compared to previous ones.
Out of all of the new projects listed below, I’m most excited about the Belgium ketamine/fibromyalgia study. Over the years, I’ve heard from a number of my readers who report pain relief from ketamine infusions.
However, the drawback to using ketamine is the pain relief lasts, at most, only a few weeks. Many of us with chronic pain aren’t able to access ketamine due to the ongoing cost and lack of coverage by health insurance companies.
Perhaps more research will lead to better access! Let’s hope so!
If you’ll remember, there were no new Lyme trials to report during my last quarterly update in March. I’m happy to see a few new Lyme-related projects in this update!
As you read through the trials, let me know in the comments if any of them interest you. Do you think any of these will move us forward in more understanding of fibromylagia and Lyme?
Grand Hôpital de Charleroi researchers in Belgium will trial low and high doses of S-ketamine to determine if it might relieve the pain of fibromyalgia.
Al-Azhar University researchers in Egypt are trying to determine if the heightened anxiety triggered by the COVID-19 pandemic has led to more fibromyalgia patients seeking treatment from outpatient clinics.
University of Florida researchers will study fibromyalgia patients’ sensitivity to light “using visually evoked potentials. In addition, careful characterization of experimental pain responding across multiple sensory modalities will be examined,” reads ClinicalTrials.gov.
Researchers from the University of Nove de Julho in Brazil will “investigate the effectiveness of [photobiomodulation therapy] combined with static magnetic fields in pain relief in patients with fibromyalgia.”
Istanbul University researchers in Turkey plan to compare balance-proprioception and aerobic exercises to determine if either improve pain, functionality, muscle strength and cognitive ability among 62 fibromyalgia patients.
(Read more: Fibro warrior develops exercise program just for us)
Medical benefit evaluation of ambulatory activity combining rehabilitation and therapeutic education, using an intelligent electric bike for the health, for the effort rehabilitation and the quality of life improvement for patients suffering of moderate fibromyalgia
French researchers from the Grenoble Alps University Hospital will evaluate if outdoor exercise using the Intelligent Electric Bike for Health combined with therapeutic education will improve the quality of life for fibromyalgia patients.
Biopolis S.L. will compare the effects of taking a multistrain probiotic for 12 weeks versus placebo among 50 fibromyalgia patients.
(Read more: Fibromyalgia linked to gut bacteria for first time)
Dr. Jacob Teitelbaum and the Practitioners Alliance Network will test the effectiveness of “a unique oral porcine peptide nutritional supplement” among 200 fibromyalgia patients, according to ClinicalTrials.gov.
Researchers from Italy’s Fondazione Policlinico Universitario Agostino Gemelli IRCCS will compare six weekly sessions of acupuncture to standard fibromyalgia therapy consisting of antidepressants, anti-epileptic drugs or opioids.
(Read more: Acupuncture for treating fibromyalgia)
Lyme disease studies
Adaptive Biotechnologies will test the sensitivity and specificity of its immunoSEQ DX investigational Lyme assay.
Yale University is creating a rheumatology biorepository of 5,000 patients with Lyme disease, Sjogren’s syndrome, ankylosing spondylitis, rheumatoid arthritis and similar conditions “to permit comparative analyses between the rheumatic diseases in order to increase the understanding of disease pathogenesis.”
The National Institute of Allergy and Infectious Diseases and the University of Maryland School of Medicine will partner on this “natural history study, which has the objective of developing a rigorously defined population of patients with Lyme disease and other tick-borne illnesses, per [Centers for Disease Control and Prevention] case definitions, to serve as the basis for research in multiple aspects of [tick-borne] infections. These research sub-projects have emphasis in exploring the biological markers of tick-borne infections, developing new diagnostic tests for these infections, assessing the clinical course and outcome of patients with these tick-borne infections, and defining the immunological response to the pathogens.”
The Research Foundation for Mental Hygiene, Inc. will determine if meditation/breathing techniques and/or kundalini yoga can improve the symptoms of patients with post-treatment Lyme disease syndrome and chronic Lyme disease.